Best Liver Supplements to Detox

The liver regulates many health aspects. It is vital for the optimal performance of your body and adequately detoxifies it. This is one of the many reasons why liver health is of utmost importance.

The largest organ in our body is the liver, and its size is similar to a football. It is located under the rib cage, to our abdomen’s right side.

Since the liver’s role is crucial for our health, lousy liver health may quickly influence your general health condition.

Many people turn to use supplements daily as a way to maintain their liver’s health. There are various kinds of supplements for this purpose, and they aim to improve different areas of the liver. Some of them help eradicate toxins, while others prevent inflammation.

Have you been wondering which are the most effective liver supplements that you can buy today? All you need to do is keep reading this informative article and uncover the best liver health supplements out there.

10 Best Liver Health Supplements

The team behind this article went to great lengths to discover the best liver supplements. They got in touch with manufacturers, consulted various studies, and even tested some of them.

Here follows the list of the world’s provenly most effective liver supplements:

Organifi Liver Reset

Liver Reset from Organifi is a famous liver health supplement created by one of the few prominent brands you can find on the internet. It is efficient, but it is affordable too, with monthly supply costs under $28. Organifi’s secret ingredients are a handful of superfoods that have been used to heal liver malfunctioning for hundreds of years now. Some of these include Triphala, an artichoke extract, milk thistle, dandelion root, and more.

The transparency of Organifi Liver Reset dosages makes it simple to contrast its formula with the rest of the liver health supplements found online.

Organic ingredients are also included in the product. Some offer 250 mg of organic milk thistle seed extract and 300 mg of organic dandelion root and Triphala extracts. The supplement also boasts a modest price of $27,95.

1MD LiverMD

This liver supplement may be the most easily accessible from the list. You can buy it online from Amazon or the official site. If you aren’t a fan of online shopping, you can always go to the nearest store, such as Walmart, and get it there.

This supplement’s main ingredients are 100mg of ALA, 800mg of NAC, and potent doses of essential minerals and vitamins, such as Vitamin E, selenium, and zinc. A bottle of 1MD Liver MD costs $45 and consists of clinically-tested liver health ingredients, such as an extract of milk thistle.

1MD LiverMD is one of 1MD most popular supplements available nowadays. But, they also make an array of other supplements which help regulate other health and wellbeing goals. 1MD is undoubtedly one of the best liver health supplements you can buy today. You can determine the proper dosage via a doctor’s consultation, and you will most definitely experience positive results. The product is available at a reasonable cost of $44.99.

LiverWell from Live Conscious

Happy Liver – Happy Life is the slogan Live Conscious swears by. The company’s LiverWell supplement helps kickstart the metabolism and the liver, using natural-only ingredients. The benefits of taking two pills per day are wholesome liver protection and detoxification, healthy immune cells, and improved metabolism.

All ingredients connected to liver health are constituents of LiverWell. Such include milk thistle extract, ALA, and NAC. The best part is that this supplement comes with probably the most affordable price on the list, or $25.99 per bottle.

Amy Myers MD Liver Support

Liver Support is produced by Amy Myers MD and features a mixture of ingredients that assist with detoxification and liver function optimization. The supplement boasts 200mg of NAC that serves as an antecedent to glutathione. To help rummage free radicals, the supplement contains alpha-lipoic acid.

Amy Myers MD’s recommended dosage is one capsule of Liver Support per day. The product ingredients will fully detox your body and improve overall liver function. While not the cheapest of all supplements, the Amy Myers MD Liver Support still comes at a fair price of $34,97.

Zenith Detox by Zenith Labs

Zenith Labs produces a doctor-formulated supplement called Zenith Detox. The company assures this supplement supports overall liver health while simultaneously supporting 1 and 2 healthy phases of detoxification. One capsule a day will provide your body with the necessary ingredients to maintain healthy liver function and eradicate free radicals.

According to the Zenith Detox expert doctor’s opinion, the supplement can also reduce pain in the joints, improve physical stamina, resulting in a fresher and more youthful physical appearance, and increase assertiveness. The Zenith Labs supplement also contains ingredients usually unseen in other products. Such are constituents of other supplements, like L-methionine, Setria glutathione, and an extract of Schisandra berry. Thanks to this handpicked ingredient list, the product comes at a higher cost of $49.

Gundry MD Complete Liver Support

Gundry MD’s Complete Liver Support supplement is the most affordable one of all on the list. You can buy it for less than $20 a bottle, and it is regarded as your liver’s “Swiss Army Knife.” Gundry MD assures its buyers that Liver Support will improve the overall absorption of nutrients, support both the metabolism and the immune system, and assist your body in the natural fight against environmental toxins.

An extract of 1000mg from orange peel is the product’s main ingredient. As a unique compound, it can’t be found in other supplements included in our list. The additional formula ingredients are dandelion and milk thistle. The current supplement cost is $19.48.

Advanced Liver Support by Advanced Bionutritionals

Advanced Bionutritionals produce the Advanced Liver Support supplement. Its main ingredients include phosphatidylcholine, selenium, NAC, ALA (alpha-lipoic acid), milk thistle, and glycyrrhizin.

The company claims that taking four capsules from the supplement a day will bring more benefits than expected. These include general brain and liver health, healthy inflammation response, and liver protection from oxidative stress. This reliable supplement is produced in the USA, with the help of globally sourced ingredients, with a price of $39.95

PureHealth Research – Liver Health Formula

A naturopathic doctor developed this Live Health Formula supplement from PureHealth Research. The ND (naturopathic doctor) assures that the Liver Health Formula supplement will “recharge your body’s youth battery” while also giving you “limitless energy, sharp thinking, and the desired trim waistline.”

Alfalfa, beet, and ginger are the essential ingredients of the Liver Health Formula. Some of the most popular constituents of liver health supplements are also included in the product. Such are milk thistle, as well as artichoke, dandelion, and turmeric extracts, and more. Given its potency, the supplement boasts a price of $49 a bottle.

Morning Complete – ActivatedYou

Morning Complete by ActivatedYou is probably the only supplement that made it to the list without being mainly presented as a liver health supplement. However, it’s better than that since Morning Complete is an all-encompassing health supplement needed for a daily dose. Its formula consists of green superfoods, fiber, prebiotics, and probiotics, as well as other ingredients that contribute to your overall health.

“A potent daily wellness drink” is how ActivatedYou describes morning Complete.

Among other acquired benefits, a daily dosage will help your immune system fight off oxidative stressors. It will also improve healthy cell and liver functioning and contribute to balanced blood sugar levels. It is also one of the priciest supplements on the list, with a tag of $79.

VitaPost Liver Support Plus

Here’s another supplement that almost everyone can afford to buy – Liver Support Plus by VitaPost, whose bottle costs less than $28. This liver supplement can also be purchased at Walmart or other retailers, just like LiverMD by 1MD.

A bottle of Liver Support Plus contains ingredients such as beet, zinc, extracts from artichoke and milk thistle, and celery seeds.

This supplement is different from the rest of the list because it contains many ingredients. All these are integrated at lower dosages. Liver Support Price can help maintain the liver healthy while still maintaining an affordable selling price. The cost per bottle of the supplement is $27.95.

Urgent Liver 911 by Phytage Labs

Phytage Labs created a nutritional supplement called Urgent Liver 911. It contains specific ingredients known to protect liver health in distinctive ways. This supplement consists of celery seeds and extracts from milk thistle and dandelion, artichoke, and beetroot.

Urgent Liver 911 shares the same list of ingredients with the previously mentioned Liver Support Plus.

Phytage Labs advises customers to take Urgent Liver 911 daily. This is because the 23 encompassed ingredients will contribute to the overall health of the liver. The benefits of taking the supplement daily include losing the fat that might clog the liver and detoxify it.

The price per bottle is almost $70, which gives Urgent Liver 911 a relatively lower value than the rest of the listed liver supplements. This comes as a surprise when one considers the somewhat low dosages. A bottle of this supplement will cost you $69.95

Bonus Reading Material: The Non-Alcoholic Fatty Liver Disease Solution

Taking supplements won’t suffice in the long run to keep your liver healthy. Healthy lifestyle habits and a suitable diet are just as essential to implement.

Here, we present Julissa Caly from Blue Heron Health News and her expert opinion on naturally maintaining a healthy liver. Heron Health News advertised this e-book as the “ultimate solution” to NAFLD (non-alcoholic fatty liver disease). It is an illness triggered by the building up of triglycerides in the liver.

In her book, Julissa labels fatty liver disease as being a “choice,” not a “prison sentence.” Following her recommended treatment plan, anyone can try their best to “make themselves well again” and “melt away the liver fat.” Yes, even the ones who suffer from a more severe form of NAFLD. Cost: $49

How We Ranked The 10 Best Liver Health Supplements

After researching liver support supplements, we realized that they all claim to support the liver in many aspects. As expected, some of these do help, while others don’t contribute as much as advertised. To make a distinction between the best and the worst, we employed the ranking methods that follow.

Tested Ingredients

We took into consideration loads of scientists’ published studies on selective ingredients. Such include minerals, vitamins, plants, and herbal extracts, all aiming to help improve liver health. We made sure to list supplements that used this type of extensive knowledge when building their formula.

Clinically-Proven Effective Dosages

There are numerous supplements out there, some of which contain low dosages. Others, however, use all the right ingredients, but often in the wrong dosage. Some brands include doses that aren’t even sufficient to affect the body at all. During our research, we looked for supplements with clinically effective doses.

Formulated by Doctors

We tended to include supplements produced by companies who always consult doctors when creating their formulas. MDs, NDs, and other healthcare professionals should contribute their medical expertise when making the most effective liver health supplements.

Advertised Benefits

Some companies exaggerate when advertising their products. They tend to claim that the supplement formula will heal the body entirely and provide whole-body detoxification. Some idealistic results that companies present are looking way younger compared to before taking the supplement. Moreover, the remaining benefits include weight loss or curing severe liver disease. We added companies that advertise realistic effects and sincere health benefits.

Manufacturers’ Prestige

We preferred eminent, reputable manufacturers. This is because many producers of supplements on the market seem to be a bit suspicious. Our team was on the lookout for transparent production companies only – once transparent about their production process and location.

Value and Cost

Not everyone is willing to pay the same amount of money for liver health supplements. Some are ready to spend about $20 per month, while others can afford much more than that. That’s why we compared the prices of the products and their value, so you have more viable and budget-friendly options to consider.

Benefits of Liver Health Supplements: What Does Science Say?

Many studies have endorsed minerals, vitamins, herbal extracts, and plants to help maintain liver health. Some of these natural remedies have been taken by people for hundreds of years now.

In the next section, you’ll find some evidence on the effectiveness of supplement ingredients on liver health.

Milk Thistle

Milk thistle is probably the most well-known liver health supplement ingredient. People have been using liver health supplements to treat their liver diseases for over 2,000 years. Today’s most significant number of supplements sold in the USA consists of a milk thistle extract, among other ingredients. This is because milk thistle contains silymarin, a compound found to help regenerate liver tissue. It also reduces inflammation, while its antioxidant effects prevent liver cell damage.

Artichoke Leaves

Artichoke Leaves are another popular ingredient of a liver health supplement. The artichoke shares the same benefits as the milk thistle. Therefore, according to some studies, it boasts plenty of antioxidant qualities that can help protect the liver.

The artichoke leaf was proven to help in the regeneration of the liver cells during an animal-tested study. Moreover, this study, conducted in 2018, suggests that artichoke leaves are proven to be helpful for patients struggling with non-alcoholic fatty liver disease. When contrasted to patients who took placebo pills, artichoke leaf showed to be quite valuable for supporting liver health.

Dandelion Root

Dandelion Root is another ingredient found in many liver supplements. However, dandelion’s effectiveness on liver health isn’t as investigated as the ones of milk thistle and artichoke leaves. Up until today, there are no extensive studies on humans regarding the effects of the dandelion root. There is, though, an article published in the Journal of Ethnopharmacology. In it, researchers have found the dandelion to be studied primarily for its anti-inflammatory and anti-oxidative qualities but also its anti-carcinogenic properties.


Zinc is a vital mineral that is needed for several functions in our body. Such include DNA synthesis, cell division, and immunity functions, among others. Some liver health supplements list zinc among its active ingredients. People who suffer from chronic liver disease are at a higher risk of lacking zinc in their bodies. There is a study from 2012 stating that taking a suitable dosage of zinc daily can protect the liver from the damage that hepatitis C viral infections cause. Except for this study, there are only a couple of bigger ones related to zinc and its positive effects on liver disease.

Licorice Root

Licorice root is another ingredient often enlisted among other ingredients of liver health supplements. The effect of licorice has been proven during a study in 2012 when 379 people diagnosed with chronic hepatitis C were given this root. Interestingly, all of them noticed a significant decrease in the symptoms of hepatitis C compared to the other control group. Moreover, another study on rats suggested that a licorice root extract helped reduce inflammation caused by alcohol and liver fat accumulation. However, additional studies have to be performed on humans to prove the actual effectiveness of licorice. The National Health Institute warns that overusing licorice can be harmful because it contains a high amount of glycyrrhetinic acid. This is the reason why some supplements list DGL (deglycyrrhizinated licorice) as an active ingredient.


Turmeric is very famous among ingredients that help contain a healthy liver. People take it daily because it maintains overall liver health. A study shows that an active ingredient in turmeric, curcumin, contributes to a healthy liver in many aspects. The same research also suggests that people who took 3g of turmeric daily have improved their liver health compared to placebo pills. Another essential feature that researchers discovered is that turmeric substantially reduced serum alanine transaminase (ALT) levels. The same applies to aspartate aminotransferase (AST) levels. This occurred with no detrimental reactions, contributing to the suggestion that turmeric “may help improve hectic disorders,” as stated by some researchers.

Yellow Dock Root

Among the not-so-well-known liver health supplement ingredients is the yellow dock root. Still, there have been studies that suggest that this root helps optimize general liver health. People believe that yellow dock root has unbelievable detoxification potency. One can mostly find it in Essiac tea, which is a traditional formula beneficial for blood cleansing. On the other hand, researchers have claimed that this root does have diuretic effects, making you urinate more frequently than usual. The yellow dock root also triggers peristalsis and might increase the excretion of mucus from the colon. Thus, it helps with the removal of waste from your body. An ingredient called anthraquinones is contained in this yellow dock root, which could help support liver health.

Other Ingredients

ALA (Alpha-lipoic acid), molybdenum, choline, selenium, beetroot, ginger, and various other ingredients are often related to improving the liver’s health. All of these may be included in some supplements in small doses. Others, however, have only a selected few ingredients in more potent doses.

Early Liver Issue Symptoms

The liver is one of the most vital and most extensive organs in your body. It performs some crucial functions that contribute to your overall performance and lifestyle. Suffering from poor liver health can be detrimental to your general wellbeing. Some people might be facing a problem of such and still be unaware of it.

Read some early signs of a defective liver:

  • Appetite loss
  • Urine is dark yellow or gray stools
  • Fatigue
  • Vomiting or nausea
  • Uneasiness or pain below your ribs, in the upper right part of the abdomen

If you have some more severe liver problems, you are expected to experience some more severe symptoms. Some of these could include:

  • Continuous bleeding or easy bruising
  • Retention of fluid
  • Cognitive problems or confusion
  • Mood swings
  • Forgetfulness
  • Yellow eyes or skin (jaundice)

Everything can be treated if caught on time. So, it’s advisable to see a doctor if you experience anything of the abovementioned.

Best Ways to Support Liver Health

Taking a supplement is always a go-to option. However, practicing a healthy lifestyle and consuming suitable products will help you maintain your health in the long run. By implementing these features, you will most likely preserve your liver as healthy as possible.

Read some of the top science-supported ways to maintain liver health below:

Weight Loss

Fat is harmful to your liver, especially the consumption of saturated fat. Cholesterol and high levels of triglycerides can contribute to fat accumulation, which leads to NAFLD (non-alcoholic fatty liver disease). This disease is often related to persistent liver damage.

Supplement Consumption

Consult our list of liver supplements and decide which one works the best for your needs. Whether you need to treat inflammation or detoxify the body, many supplements are created for your problem.

Minimize Alcohol Consumption

Alcohol is regarded as a harmful poison. What’s worse, your liver metabolizes it to assist your body in its processing. In this process of metabolization, the liver releases toxic chemicals, such as acetaldehyde. An activity known as binge drinking, which means drinking more than three drinks over two to three hours, can contribute to a condition known as steatosis.

This happens when fat accumulates inside liver cells. All in all, reducing alcohol intake will only be helpful for the welfare of your liver.

Minimize Smoking

Toxins enter your body very fast when you smoke, and this tobacco smoke significantly damages your liver. When your liver purifies the toxins from your body, it can create liver inflammation or other liver problems.

Reduce Toxins Exposure

Whether we like it or not, toxins are all around us. They’re in the cleaning products we use, the food we eat, the water we drink, etc. Managing to reduce exposure to toxins will surely improve your overall liver health.

Don’t Use Illegal Drugs

Cocaine and heroin are explicitly related to liver damage and inflammation.

Minimize Medication Intake

Taking too many prescribed medications or even over-the-counter ones could contribute to additional liver problems. According to the FDA, antibiotics, cancer medication, anti-anxiety pills, acetaminophen, and immunosuppressant drugs cause liver damage. Please consult your doctor for any of the medicines you decide to take, and most importantly, don’t overuse any of them.

Liver Health Supplements FAQs

Q: What are liver supplements?

A: Liver supplements are products created with natural ingredients that support liver health.

Q: What is a liver?

A: The largest organ in our body is the liver, and its size is similar to a football. It is located under the rib cage, on our abdomen’s right side.

Q: How do liver supplements work?

A: Most often, liver supplements help with detoxification of the liver and kidneys, maintaining an overall healthy liver, and assisting the immune system.

Q: Which one is the best liver health supplement?

A: You won’t make a mistake choosing any of the supplements included in our lists, as they are some of the best in the world.

Q: What’s the function of the liver?

A: The liver is dedicated to performing many vital functions in the body. These include processing nutrients, destroying unwanted blood cells, producing crucial blood-clotting chemicals, regulating body composition, regulating and metabolizing alcohol and drugs, creating necessary cholesterol and proteins, and many others.

Q: What contributes to liver damage?

A: Practicing an unhealthy lifestyle and consuming unhealthy food can lead to liver damage. The same applies to excessive consumption of medication, alcohol, tobacco, and even hepatitis – all of which can cause liver damage.

Q: Is having a liver disease genetic?

A: Some liver diseases are genetic, while a bad diet and unsuitable lifestyle trigger others.

Q: What can cause liver issues other than alcohol?

A: Even though alcohol is believed to be the primary factor in liver damage, the overuse of medication, an inconvenient diet, toxin exposure, or even eating undercooked shellfish can cause liver damage.

Q: What are the symptoms of liver issues?

A: Weariness, tiredness, bloating, yellow eyes/ skin, gas, high blood pressure, mood swings, dark yellow urine, abnormal sweating, and poor appetite are symptoms of having liver issues.

Q: How to cleanse the liver?

A: There are various ways. Some people exercise regularly to assist the body with its natural cleansing process. Others take supplements or follow a strict diet for a few weeks. Another way is to stop consuming toxic foods or stopping unhealthy habits.

Q: Which are liver disease symptoms?

A: Symptoms of such a disease may include fatigue, body itching, or lack of motivation. With the advancement of the disease, you might notice jaundice (yellow eyes/ skin), excessive bleeding, dark urine, cognitive problems, as well as fluid retention.

Q: How can I know for sure if I have liver disease?

According to a study at the University of Iowa, 50% of people who suffer from liver disease have no apparent symptoms. Do the necessary testing and consult your doctor to determine your liver condition.

Q: Can liver damage be reversed?

A: The liver is an outstanding organ and one of the few in our body that can regenerate itself, like the heart. Unlike the heart, it replaces the defective tissue with new cells, which replaces those tissues with scars. The University of Iowa states that even 50 to 60% of damaged liver cells can be regenerated completely (even if caused by Tylenol overdose, for example). That is, again, if there are no unwanted complications during the process.

Q: Do I need a liver supplement?

A: You can consult your doctor if you are not sure whether you need a liver supplement. It’s advisable to do so in any case, especially if you already have liver disease or are under ongoing medication treatment.

Q: What’s the most common reason for liver disease in the USA?

A: Excessive alcohol consumption is the most common cause of liver disease in the United States.

Q: Is the liver the biggest organ in our body?

A: The liver is the second largest after the skin or the most considerable body organ.

Q: Is hepatitis a type of liver disease?

A: Yes, it is. The word ‘hepatitis’ means “inflammation of the liver,” a type of liver disease.

Q: What is cirrhosis?

A: The liver is known to be able to repair its damaged cells. Yet, cirrhosis is a chronic liver disease that happens when the body tries to repair the liver – without repairing cells. This way, scar tissue continuously builds on the liver. This ultimately leads to a late-stage disease known as cirrhosis.

Q: How do doctors test liver health?

A: Doctors might perform several blood tests simultaneously to do a liver health check, using a liver function panel. This way, they can spot hepatitis (liver inflammation), liver disease, and other liver defectiveness.

Q: Should liver detox be performed regularly?

A: There’s no scientific proof that performing detoxification of the liver will help its overall functioning. It’s pretty simple. Your body should automatically detoxify itself if your liver is functioning correctly. Have in mind, though, that a suitable lifestyle and healthy diet will improve the functioning of your liver.

Q: What are the best food products for a healthy liver diet?

A: There isn’t a predetermined liver health diet that suits everyone. Still, doctors usually recommend eating Mediterranean products to those suffering from liver disease, emphasizing various fruits and vegetables.

Q: Do liver supplements help?

A: Many studies suggest that well-known ingredients primarily found in liver supplements can support and improve the general behavior of the liver. Some of them are milk thistle, turmeric, and an extract of artichoke leaf. Most of them help by supporting liver inflammation.

Q: Is it safe to take liver supplements?

A: Several studies have proven that liver supplements are only safe when taken in the recommended dosages. It’s best to speak with your doctor before deciding to start any of the supplements. More importantly, consult a professional if you are already taking another medication.

Q: Can the supplements harm my liver?

A: Most probably not. If you follow and take the suitable dosage prescribed to you, you are unlikely to experience any unwanted impact on your liver health. Still, studies suggest that 20% of all liver injuries are related to herbal supplements.

Q: What is a fatty liver?

A: A fatty liver is a revocable condition that features triglycerides (fat particles) in the same cells of the liver. This condition can be triggered by an array of diets, genetics, or an inconvenient lifestyle. It’s good to know that this fatty liver condition doesn’t have the possibility of turning into cirrhosis.

Q: What is NAFLD?

A: NAFLD stands for non-alcoholic fatty liver disease. It is a scope of liver problems, starting from minor ones and possibly continuing to severe conditions like cirrhosis. The building up of liver fat is standard for all of the NAFLD.

10 Best Liver Health Supplements Conclusion

Various studies show that there are natural ingredients that genuinely help support liver health in many diverse ways. These include artichoke extract, zinc, milk thistle, and other compounds that reduce inflammation in the liver while assisting in its cleansing and general wellbeing.

Everyone interested in supporting the health of their liver should think about taking a supplement. You can always go back to the list we prepared for you and choose vetted and proven options.


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